Onychomycosis caused by Aspergillus terreus

Four cases of onychomycosis caused by Aspergillus terreus are presented. The clinical characteristics consisted of spotted and striated leuconychia, dark spots and fragility of the nails. The mycology is described, and is shown that A. terreus has an inhibitory effect on the growth of dermatophytes and Scopulariopis brevicaulis. Topical treatment with 1% Pimafucin in a mixture of 60% dimethylsulfoxide (DMSO) and 40% water as well as 9% aqueous solution of sodium benzoate were both effective. The literature concerning onychomycosis caused by A. terreus is summarized.