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Related Experiment Videos

Onychomycosis caused by Aspergillus terreus.

P Onsberg, D Stahl, N K Veien

    Sabouraudia
    |March 1, 1978
    PubMed
    Summary

    This study details four cases of nail fungus (onychomycosis) caused by Aspergillus terreus. Effective topical treatments included Pimafucin with dimethylsulfoxide (DMSO) and sodium benzoate.

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    Area of Science:

    • Medical Mycology
    • Dermatology

    Background:

    • Onychomycosis is a common nail infection.
    • Aspergillus species are increasingly recognized as causative agents of onychomycosis.

    Observation:

    • Four cases of onychomycosis attributed to Aspergillus terreus are presented.
    • Clinical signs included spotted/striated leuconychia, dark spots, and nail fragility.
    • Aspergillus terreus demonstrated inhibitory effects on dermatophytes and Scopulariopis brevicaulis growth in vitro.

    Findings:

    • Topical treatment with 1% Pimafucin in a 60% dimethylsulfoxide (DMSO) and 40% water mixture was effective.
    • A 9% aqueous solution of sodium benzoate also proved effective in treating these cases.
    • The study summarizes existing literature on Aspergillus terreus onychomycosis.

    Implications:

    • Highlights Aspergillus terreus as a pathogen in onychomycosis.
    • Suggests novel and effective topical treatment options for challenging nail fungal infections.
    • Informs clinical practice regarding diagnosis and management of Aspergillus-related onychomycosis.

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