Related Experiment Videos
[Upper digestive hemorrhage, physiopathologic and therapeutical considerations]
I Costea1, M R Diaconescu, R Terinte
1Facultatea de Medicină Stomatologică Clinica a IV-a Chirurgie, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Summary
This study analyzed 158 patients with upper digestive hemorrhage (UDH), finding that drug therapy effectively achieved hemostasis in most cases. Surgery was reserved for severe bleeding or elective procedures for ulcers and gastric carcinoma, with good postoperative outcomes.
Area of Science:
- Gastroenterology
- Surgical Gastroenterology
- Internal Medicine
Context:
- Upper Digestive Haemorrhage (UDH) presents a significant clinical challenge.
- Analysis of 158 patients admitted between 1998-2002.
- Focus on physiopathological mechanisms of ulcer bleeding.
Purpose:
- To analyze the causes, management, and outcomes of Upper Digestive Haemorrhage.
- To evaluate the efficacy of drug therapy and surgical interventions.
- To understand the role of different etiologies in UDH.
Summary:
- Gastro-duodenal ulcers were the most common cause (76%), followed by portal hypertension (20%), gastric carcinoma (8.8%), and rare etiologies (5.4%).
- Hemostasis was successfully achieved with drug therapy in the majority of patients (94.6%), with surgery indicated for severe bleeding (6%) or elective procedures (55%).
- Postoperative outcomes were generally favorable, with a low mortality rate (1.2%) primarily associated with severe UDH from ruptured esophageal varices in cirrhotic patients.
Impact:
- Highlights the effectiveness of conservative management for most UDH cases.
- Provides insights into the surgical indications and outcomes for specific UDH etiologies.
- Contributes to understanding the overall prognosis and management strategies for upper gastrointestinal bleeding.