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[Determination of urinary iodine as a marker of iodine deficiency]
Mihaela Maftei1, Didona Ungureanu, Carmen Vulpoi
1Disciplina de Biochimie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Insights
Iodine deficiency persists in Moldavian school children despite prophylaxis programs. Further public health education and preventative measures are crucial for affected regions.
Area of Science:
- Endocrinology
- Public Health
- Nutritional Science
Context:
- Iodine deficiency disorders (IDD) remain a global health concern.
- Assessing iodine status in school-aged children is vital for monitoring public health.
- Moldavia's iodine prophylaxis program effectiveness required evaluation.
Purpose:
- To determine urinary iodine levels (ioduria) in school-aged children.
- To establish the prevalence and severity of iodine deficiency in four Moldavian counties.
- To inform public health strategies for iodine deficiency reduction.
Summary:
- Urinary iodine was measured in 927 children (7-14 years) from Suceava, Iaşi, Neamţ, and Botoşani counties using cerium-arsenate and semi-quantitative methods.
- Median ioduria levels indicated moderate iodine deficiency in Suceava and Roman-Neamţ, and mild deficiency in Iaşi and Botoşani.
- 93.75% of samples in Roman-Neamţ had ioduria below 10 micrograms/dL.
Impact:
- The study highlights the continued presence of iodine deficiency in Moldavia.
- Findings underscore the need for enhanced sanitary education and iodine prophylaxis measures.
- Results provide data for targeted public health interventions to combat IDD in the region.
Purpose:
Determination of ioduria in order to establish the actual degree of iodine deficiency in school-age children from 4 counties in Moldavia.
Materials And Methods:
Urinary iodine was determined in 927 school-children aged 7-14 years from 4 counties: Suceava, Iaşi, Neamţ and Botoşani. The determination was made by cerium-arsenate method and by a semi-quantitative method.
Results:
The median value of ioduria was 3 micrograms/dL in Suceava, 8.8 micrograms/dL in Iaşi, 7.1 micrograms/dL in Botoşani. In Roman-Neamţ 93.75% of all samples had a value of ioduria below 10 micrograms/dL. From this point of view, Suceava and Roman are with moderate iodine deficiency; Iaşi and Botoşani are with mild iodine deficiency.
Conclusions:
Despite the existence of a program of iodine prophylaxis, there are still many regions in Moldavia with iodine deficiency, so it is important to have more measures of sanitary education and prophylaxis in these regions.
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