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Updated: Aug 29, 2026

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
Published on: April 18, 2025
[Functional MRI of the elderly can complete the picture of cerebral functions]
Harriet Nyström1, Patrizia Vannini, Lars-Olof Wahlund
1Karolinska sjukhuset, Stockholm.
Abstract:
Functional Magnetic Resonance Imaging, fMRI, is a method for the study of neuronal circuits underlying cognitive, sensory, emotional and motor activities in the living human brain. An important question is whether elderly persons and patients with cognitive deficits differ from others as regards neuronal activation. Not many studies have been published but some of them have shown surprising results. This new research has shown some very interesting new facts about the vascular response and the regulation of the microvasculature in the brain. Most fMRI studies have been performed on healthy young males, but in our opinion this method could reveal new findings to complete the picture of human cognition if studies were to be performed involving elderly people and patients with dementia.
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Magnetic Resonance Imaging
Brain Imaging
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).