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Desquamative inflammatory vaginitis.

Ruth Murphy1

  • 1Department of Dermatology, Chesterfield Royal Hospital, Chesterfield, Derbyshire, UK. Ruth.Murphy@kandc.demon.co.uk

Dermatologic Therapy
|February 6, 2004
PubMed
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Desquamative inflammatory vaginitis (DIV) is a disabling condition that may signal underlying blistering disorders. This article discusses the controversial idiopathic subset of DIV and its treatment.

Area of Science:

  • Gynecology
  • Dermatology
  • Pathology

Background:

  • Desquamative inflammatory vaginitis (DIV) is a rare, disabling condition characterized by vaginal inflammation.
  • DIV can be a symptom of various blistering disorders, including pemphigus vulgaris, lichen planus, and mucous membrane pemphigoid.
  • The existence of an idiopathic subset of DIV is debated.

Purpose of the Study:

  • To discuss desquamative inflammatory vaginitis (DIV) as a potential manifestation of blistering disorders.
  • To explore the controversial concept of an idiopathic subset of DIV.
  • To review the clinical presentation, diagnostic findings, and treatment of DIV.

Main Methods:

  • Literature review and discussion of clinical cases.
  • Analysis of diagnostic criteria for DIV and related blistering conditions.

Related Experiment Videos

  • Evaluation of treatment outcomes for DIV.

    • Main Results:

    • DIV presents with vaginal erythema and increased, purulent discharge containing polymorphonuclear leukocytes and immature squamous cells.
    • Cultures are consistently negative for infectious agents, indicating a sterile inflammatory process.
    • Successful treatment has been reported with topical steroids and clindamycin.

    Conclusions:

    • Desquamative inflammatory vaginitis (DIV) is not a standalone diagnosis but often indicates underlying blistering disorders.
    • The idiopathic form of DIV remains controversial, requiring careful differential diagnosis.
    • Prompt diagnosis and appropriate treatment, including topical steroids and clindamycin, are crucial for managing DIV symptoms.