Related Experiment Videos
[Ischaemic stroke in two children with HIV-1]
Cristiane Rocha1, Aída T B Gouvêa, Daisy M Machado
1Hospital Santa Marcelina, São Paulo, SP, Brasil. cri.rocha2@ig.com.br
Arquivos De Neuro-Psiquiatria
|February 6, 2004
Summary
Human immunodeficiency virus (HIV) infection can cause pediatric cerebrovascular issues. Early diagnosis and treatment are crucial for managing neurological complications in children with HIV.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Cerebral ischemia from inflammatory vasculopathies is a known complication of human immunodeficiency virus (HIV) infection.
- Pediatric HIV infection can present with diverse neurological manifestations.
Observation:
- Two preschool boys with new-onset HIV-1 infection presented with fever, seizures, hemiparesis, and altered consciousness.
- Serial imaging confirmed middle cerebral artery infarction in both cases.
Findings:
- One child developed severe spastic tetraparesis and epilepsy, with no improvement despite antiretroviral therapy.
- The second child experienced hemiparesis and global aphasia, with complete recovery after two years of antiretroviral and rehabilitation therapies.
Implications:
- HIV infection should be considered in the differential diagnosis of pediatric cerebrovascular events.
- Prompt diagnosis and tailored treatment, including antiretroviral therapy and rehabilitation, are vital for improving outcomes in pediatric HIV patients with neurological complications.