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Fluoride availability and stability of Japanese dentifrices
Lina Naomi Hashizume1, Ynara Bosco de Oliveira Lima, Yoko Kawaguchi
1Department of Preventive and Social Dentistry, Faculty of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. lhashizume@yahoo.com
Journal of Oral Science
|February 7, 2004
Summary
Japanese fluoride toothpastes remain effective for preventing dental caries, despite some formulations showing fluoride instability over time. Soluble fluoride levels in these products are sufficient for caries prevention.
Area of Science:
- Dental Public Health
- Fluoride Chemistry
- Materials Science
Background:
- Dental caries decline in industrialized nations is linked to widespread fluoride use.
- Japanese market share of fluoride dentifrices rose significantly from 1985 to 2000.
- Effective fluoride dentifrices require adequate soluble fluoride concentrations.
Purpose of the Study:
- To evaluate fluoride availability and stability in popular Japanese dentifrices.
- To assess the impact of calcium phosphate abrasives on fluoride in toothpaste formulations.
Main Methods:
- Analysis of total and soluble fluoride in fresh and aged (1 year) dentifrice samples.
- Use of an ion-specific electrode for fluoride determination.
- Storage of samples at room temperature (21.8 ± 3.6°C).
Main Results:
- All dentifrices met Japanese legislation limits (<1,000 ppm F).
- Some dentifrices with dicalcium phosphate showed decreased soluble fluoride and increased insoluble fluoride over time.
- Total fluoride concentrations remained consistent between fresh and aged samples.
Conclusions:
- Most evaluated Japanese fluoridated dentifrices contain fluoride with some instability.
- Despite instability, most products maintain sufficient soluble fluoride for effective caries prevention.
- Formulation with dicalcium phosphate may affect fluoride stability in dentifrices.