Related Experiment Video
Updated: Aug 29, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
Published on: March 27, 2026
Autologous transfusion in acetabuloplasty in children
P Nicolai1, P P Leggetter, P R Glithero
1Royal Orthopaedic Hospital, The Woodlands, Bristol Road South, Northfield, Birmingham B31 2AP, England, UK.
Insights
Using a pediatric cell saver significantly reduced the need for homologous blood transfusions in children with cerebral palsy undergoing hip surgery. This method avoided transfusions in 82% of patients, offering a safe alternative.
Area of Science:
- Pediatric Orthopedic Surgery
- Transfusion Medicine
- Biomedical Engineering
Background:
- Cerebral palsy (CP) often requires surgical intervention, such as acetabuloplasty for hip dysplasia.
- Blood transfusions are common in these procedures, carrying risks and costs associated with homologous blood.
- Autologous blood recovery systems offer a potential solution to minimize homologous blood use.
Purpose of the Study:
- To evaluate the efficacy and safety of a pediatric cell saver system in reducing homologous blood transfusions during acetabuloplasty in pediatric CP patients.
- To compare the volume of autologous and homologous blood transfused between the cell saver group and a control group.
Main Methods:
- A prospective study involving 22 pediatric patients (aged 6-17 years) with CP undergoing acetabuloplasty.
- Eleven patients received intraoperative autologous blood reinfusion using a pediatric cell saver.
- A control group of 11 patients received only banked homologous blood transfusions.
Main Results:
- The cell saver group received an average of 432 ml of autologous blood, significantly less homologous blood (2 units) compared to the control group (909 ml, 20 units).
- Autologous blood constituted 19.6% of total blood volume in the cell saver group versus 47% homologous blood in the control group.
- Homologous blood transfusion was avoided in 82% of patients utilizing the pediatric cell saver, with no reported complications.
Conclusions:
- Pediatric cell saver technology is effective in reducing homologous blood transfusion requirements in children with cerebral palsy undergoing hip surgery.
- The use of cell saver is a safe and viable alternative to homologous blood transfusion in this patient population.
- This approach minimizes exposure to banked blood and associated risks, improving patient outcomes.
Abstract:
There were 22 patients with cerebral palsy aged six to 17 years who underwent an acetabuloplasty as part of an open reduction of the hip. In 11 patients a paediatric cell saver was used to collect autologous blood which was re-infused per-operatively. This group was compared to a cohort of 11 patients undergoing similar operations in whom only banked homologous blood was transfused. On average, 432 ml of autologous blood was reinfused compared to 909 ml of homologous blood (p < 0.01), representing 19.6% and 47% of the total blood volume, respectively (p < 0.002). Two units of homologous blood were transfused in the cell saver group compared with 20 units in the control group (p < 0.001). When using a paediatric cell saver, homologous blood transfusion was avoided in 82% of patients and there were no complications.
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant II: Surgical Procedure
