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Updated: Aug 29, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Acromegaly. Treatment of the causal factor and the oral sequelae]
R A Feelders1, E J Delwel, C de Baat
1Afdeling Inwendige Geneeskunde, Erasmus Medisch Centrum, Postbus 2040 3000 CA Rotterdam.
Abstract:
During the last few years, a 64-years-old man experienced a progressive enlargement of his hands, feet, and tongue and an alteration in the position of his frontal teeth. In a university medical clinic acromegaly was diagnosed, based on external features, serum tests, and an oral glucose tolerance test. A pituitary microadenoma was discovered. The most common oral features of acromegaly are a prognatic mandible, interdental spaces, macroglossy, and everted, swollen lips. In this article the primary treatment and the possible oral sequelae are described.
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