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10:04
Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Intestinal tuberculosis in children. Differential diagnosis and treatment]
C Sabetay1, D Enache, E Pleşea
1Clinica de Chirurgia Pediatrică, Facultatea de Medicină, UMF Craiova.
Chirurgia (Bucharest, Romania : 1990)
|February 11, 2004
Summary
Tuberculosis remains a global health priority. This study highlights intestinal tuberculosis in children, a rare extrapulmonary form, and demonstrates its curability with timely diagnosis and treatment.
Area of Science:
- Pediatric Infectious Diseases
- Gastroenterology
- Public Health Epidemiology
Background:
- Tuberculosis (TB) is a significant global health concern, with Romania facing a particularly high incidence.
- Extrapulmonary tuberculosis, including intestinal TB, represents a challenge in diagnosis and management, especially in pediatric populations.
- The study addresses the need for effective control strategies, referencing the National Programme for Tuberculosis Control (1997-2000).
Observation:
- Intestinal tuberculosis in children presents diverse forms, including peritonitic in infants and pseudotumoral in older children.
- A significant percentage (17.2%) of TB cases exhibit extrapulmonary localization.
- Potential zoonotic sources of TB infection (bovine, ovine, poultry) were investigated alongside human Koch bacillus.
Findings:
- The study analyzed 16 cases of intestinal tuberculosis in children, including rare extrapulmonary presentations.
- Histopathological examination was crucial for differentiating intestinal TB from abdominal lymphoma or carcinomatosis in 2 complex cases.
- Surgical intervention combined with histopathological diagnosis and tuberculostatic treatment yielded excellent outcomes for all patients.
Implications:
- Early diagnosis and prompt treatment, including surgical and tuberculostatic therapies, are vital for curing intestinal tuberculosis in children.
- Understanding rare extrapulmonary TB presentations is essential for pediatricians and healthcare providers.
- Further research into zoonotic TB transmission could inform public health interventions.
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