Related Experiment Video
Updated: Jul 27, 2026

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury
Published on: August 30, 2011
Resuscitation after cardiac surgery: are we ageist?
J H Mackay1, S J Powell, S C Charman
1Papworth Hospital, Papworth Everard, Cambridge, UK. jon.mackay@papworth.nhs.uk
Elderly patients undergoing cardiac surgery experienced more cardiac arrests, with lower survival rates after cardiopulmonary resuscitation. Age was less critical than illness severity in
Area of Science:
- Cardiovascular Surgery
- Critical Care Medicine
- Geriatric Medicine
Background:
- Cardiac surgery patients face risks of cardiac arrest and the need for resuscitation.
- Age and other factors influence resuscitation outcomes and 'Do Not Attempt Resuscitation' decisions.
Purpose of the Study:
- To investigate the impact of age on cardiac arrest incidence and outcomes.
- To analyze the factors influencing 'Do Not Attempt Resuscitation' orders post-cardiac surgery.
Main Methods:
- A prospective audit of 6550 open-heart surgery cases for cardiac arrest calls.
- A retrospective audit of cardiac surgical deaths without preceding arrest calls.
Main Results:
- Elderly patients (>= 70 years) had a higher incidence of cardiac arrest (3.8% vs. 2%) and lower survival post-resuscitation (33% vs. 48%).
- 'Do Not Attempt Resuscitation' orders were more frequent in elderly patients (twice as common).
- Organ system failure rates were similar between age groups when resuscitation status was determined.
Conclusions:
- While elderly patients had more cardiac arrests and 'Do Not Attempt Resuscitation' orders, illness severity, not just age, determined resuscitation status.
- The study highlights the importance of comprehensive patient assessment beyond age for resuscitation decisions.
Related Concept Videos
Cardiopulmonary Resuscitation I: Adult
Cardiopulmonary Resuscitation III: AED Use
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Aneurysm IV: Nursing Management

