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The evolution of protein domains and the organizational complexities of metazoans
1Centre for Molecular Structure and Function, Research School of Biological Sciences, Australian National University, Canberra ACT.
Current Opinion in Genetics & Development
|December 1, 1992
Abstract:
There is an increasingly heated debate on the very existence of a 'universe of exons' and on the types of genomes that existed after the RNA world. What has been lost in the excitement are the biological issues that relate to the rapid emergence of phenotypic novelties. These issues can be examined by integrating data on protein domains and genomic evolution with the geochemical and palaeontological records.