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[Evolution of the bacteria responsible for surgical infection. n 8-year study in our department]

E Trabucchi1, M Rosina, S Casiraghi

  • 1Istituto di Chirurgia Generale ed Oncologia Chirurgica, Università degli Studi di Milano.

Minerva Chirurgica
|October 31, 1992
PubMed

Insights

Surgical infection bacteria monitoring revealed a rise in Gram-positive strains over time. Imipenem and Amikacin demonstrated the strongest antibacterial activity against these evolving bacteria.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Pharmacy

Background:

  • Surgical site infections pose significant clinical challenges.
  • Monitoring bacterial resistance patterns is crucial for effective treatment.
  • Longitudinal studies are needed to track antimicrobial susceptibility trends.

Purpose of the Study:

  • To analyze trends in bacterial strains isolated from surgical infections.
  • To evaluate antibiotic susceptibility patterns over time.
  • To identify effective antibiotics against prevalent bacterial strains.

Main Methods:

  • Bacterial strains from surgical infections were isolated and monitored from 1981 to 1988.
  • Antibiotic susceptibility testing was performed on isolated strains.
  • Data were analyzed at three distinct time points: 1981, 1984, and 1987-1988.

Main Results:

  • An increasing prevalence of Gram-positive bacterial strains was observed.
  • Imipenem exhibited high antibacterial activity in recent years.
  • Amikacin also demonstrated significant antibacterial activity in recent years.

Conclusions:

  • Gram-positive bacteria are becoming more prevalent in surgical infections.
  • Imipenem and Amikacin are effective agents against contemporary surgical isolates.
  • Continued surveillance of bacterial resistance is essential for public health.

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