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Two-dimensional gel electrophoresis analysis of Syrian hamster embryo cells: morphological transformation is not cell
R J Isfort1, G Kerckaert, N L Anderson
1Human and Environmental Safety Division, Procter & Gamble Company, Cincinnati, OH 45239-8707.
Electrophoresis
|November 1, 1992
Abstract:
Studies were conducted to investigate the protein phenotype of normal and morphologically transformed Syrian hamster embryo (SHE) cells. Based upon two-dimensional gel protein phenotype analysis, we conclude that (i) SHE cells are a mixture of multiple cell types including mesenchymal and epithelial cells and (ii) several cell types present in the SHE cell population can be morphologically transformed by a variety of genotoxic and non-genotoxic carcinogens.