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Acute lymphoblastic leukaemia presenting as breast mass
A K Jain1, R C Gupta, B Bhardwaj
1Department of Medicine, JLN Medical College, Ajmer.
Summary
A 14-year-old girl with acute lymphoblastic leukemia (ALL) experienced bilateral breast involvement. Chemotherapy led to leukemia remission and complete resolution of breast masses.
Area of Science:
- Pediatric Oncology
- Hematology
- Clinical Medicine
Background:
- Acute lymphoblastic leukemia (ALL) is a common childhood cancer.
- Breast involvement in pediatric ALL is rare but documented.
Observation:
- A 14-year-old female presented with bilateral, symmetrical breast masses.
- The breast masses were associated with a diagnosis of acute lymphoblastic leukemia.
Findings:
- Combined chemotherapy (adriamycin, vincristine, prednisolone) induced remission of ALL.
- The treatment resulted in complete resolution of the breast masses.
Implications:
- This case highlights the importance of considering leukemia in pediatric patients with breast masses.
- Effective systemic chemotherapy can resolve leukemia-associated breast manifestations.
- Further research into the mechanisms of breast involvement in ALL may be warranted.