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Medfly promoters relevant to the sterile insect technique
Katia Komitopoulou1, George K Christophides, Katerina Kalosaka
1Department of Genetics and Biotechnology, School of Biological Sciences, University of Athens, Greece.
Abstract:
This review summarizes structural and functional studies on medfly promoters and regulatory elements that can be used for driving sex-specific, conditional and constitutive gene expression in this species. Sex-specific and conditional promoters are important for generating transgenic sexing strains that could increase the performance of the Sterile Insect Technique while strong constitutive promoters are necessary for developing sensitive transgenic marker systems. The review focuses on the functional analysis of the promoters of two male-specific and heat shock medfly genes. A special emphasis is put on the potential utility of these promoters for developing transgenic sexing strains.