[Monosialoganglioside (Sygen) in amateur boxers suspended from sport activities]

Thirty boxers, suspended from sport activity for EEG alterations (delta and theta localized) and for alterations of evoked potentials (brain stem and visual potentials) have been examined after KO. Every boxer has been administered with GM1 40 mg per die for twenty days after performing the EEG with brain map, encephalic TAC, audiovestibular examination, evoked potentials. These controls (tests) have been repeated after 30 days. In particular, the cerebral mapping has been examined comparing it with significant statistic tests before and after the administration of GM1; a shift in the power spectrum of the alpha activity toward central derivation and a decrease in delta and theta activities have been observed. The hypothesis of a noradrenergic action of GM1 has been formulated.