Related Experiment Video

Updated: Aug 5, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Celiac disease incidence after COVID-19 infection

Christina Mastori-Kourmpani1, Theodosios D Filippatos2, Aris P Agouridis1

  • 1Second Department of Internal Medicine, Hippokration University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Minerva Medica
|August 3, 2026
PubMed

Insights

Coronavirus disease 2019 (COVID-19) infection does not appear to increase the risk of developing celiac disease (CD). This systematic review found no significant difference in CD incidence between COVID-19 patients and non-COVID-19 individuals.

Area of Science:

  • Immunology
  • Infectious Diseases
  • Gastroenterology

Background:

  • Auto-inflammatory diseases, including celiac disease (CD), have seen increased incidence post-COVID-19 pandemic.
  • The potential link between COVID-19 infection and CD risk requires investigation.

Purpose of the Study:

  • To systematically review and meta-analyze existing studies.
  • To assess the association between COVID-19 infection and the incidence of celiac disease.

Main Methods:

  • Searched MEDLINE, Cochrane Library, and Clinicaltrials.gov databases.
  • Conducted qualitative and quantitative syntheses of retrospective studies.
  • Included 4 studies with over 10 million participants (COVID-19 exposed and non-exposed).

Main Results:

  • Pooled analysis revealed no significant difference in CD incidence between COVID-19 exposed and non-exposed individuals (RR 1.25, P=0.12).
  • Sensitivity analysis also showed no difference in CD incidence between COVID-19 and non-COVID-19 patients (RR 1.10, P=0.06).
  • High heterogeneity (I²=87%) was noted in the initial pooled analysis.

Conclusions:

  • COVID-19 infection does not appear to elevate the risk of developing celiac disease.
  • Further research may be warranted to explore potential indirect effects or specific patient subgroups.
Abstract

More Related Videos

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Related Concept Videos

Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Amebiasis01:28

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...