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[Use of vitamins in allergic illnesses in children]
Voprosy Meditsinskoi Khimii
|September 1, 1992
Insights
High doses of vitamin B6 effectively treated allergic diseases like asthma and atopic dermatitis in children. Quercetin also showed benefits for pollinosis by improving lymphocyte lipid metabolism.
Area of Science:
- Pediatric Allergy and Immunology
- Nutritional Science
- Biochemistry
Context:
- Allergic diseases pose significant health challenges in pediatric populations.
- Nutritional interventions are explored for managing pediatric allergic conditions.
- Understanding cellular mechanisms in allergic responses is crucial for developing effective treatments.
Purpose:
- To evaluate the therapeutic efficacy of vitamins B6, P, and E in children diagnosed with allergic diseases.
- To investigate the role of quercetin in managing pediatric pollinosis.
- To assess the impact of these micronutrients on lymphocyte membrane lipid metabolism.
Summary:
- Maximal doses of vitamin B6 demonstrated enhanced therapeutic effects in children with bronchial asthma and atopic dermatitis.
- Quercetin proved beneficial for children suffering from pollinosis, specifically by correcting lymphocyte membrane lipid metabolism impairments.
- Vitamin E exhibited only slight efficacy in treating pediatric atopic dermatitis.
Impact:
- Findings suggest vitamin B6 as a potentially key therapeutic agent in managing severe pediatric allergic conditions.
- Quercetin emerges as a promising agent for addressing specific metabolic dysfunctions in pediatric allergic rhinitis.
- This research contributes to evidence-based nutritional strategies for pediatric allergy management.
Abstract:
Therapeutic efficacy of vitamins B6, P and E was studied in children with allergic diseases. Bronchial asthma and atopic dermatitis were treated more effectively if maximal doses of vitamin B6 were used. Quercetin was found to be useful for treatment of children with pollinosis in order to correct impairments in metabolism of lymphocyte membrane lipids. Only slight efficacy of vitamin E was detected in atopic dermatitis of children.