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Related Experiment Videos

Treatment of anejaculation with electroejaculation.

J Denil1, D A Ohl, E J McGuire

  • 1Department of Urology, Hannover Medical School, Germany.

Acta Urologica Belgica
|January 1, 1992
PubMed
Summary

Electroejaculation (EEJ) effectively treats male infertility from anejaculation, enabling fatherhood for men with spinal cord injury or after cancer treatment. This technique, combined with artificial insemination, offers a safe and efficient solution with a high success rate.

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Area of Science:

  • Reproductive Medicine
  • Urology
  • Neuroscience

Background:

  • Male infertility due to anejaculation is a significant challenge for men with spinal cord injury (SCI) and those who have undergone retroperitoneal lymph node dissection (RPLND) for testicular cancer.
  • Other conditions like diabetes mellitus, multiple sclerosis, and extensive pelvic surgery can also lead to neurogenic ejaculation loss, with limited treatment options available.
  • Primary absence of ejaculation is another condition affecting male fertility.

Purpose of the Study:

  • To evaluate the efficacy and safety of electroejaculation (EEJ) combined with artificial insemination (AI) for treating male infertility caused by anejaculation.
  • To assess the feasibility of obtaining viable sperm samples for AI in patients with various causes of anejaculation.

Main Methods:

Related Experiment Videos

  • Electroejaculation (EEJ) involves low-current rectal probe stimulation of ejaculatory organs to induce semen emission.
  • In non-SCI patients, EEJ typically requires general anesthesia.
  • Collected semen is processed to isolate motile sperm for artificial insemination (AI) of the partner.

    • Main Results:

    • EEJ successfully obtained ejaculates in nearly all of the 198 men treated at the University of Michigan (1986-1991).
    • A semen sample suitable for AI (≥10 million progressively motile sperm) was achieved in 75% of SCI men and 87% of RPLND patients.
    • 49 pregnancies were achieved, resulting in 35 healthy births, with an overall pregnancy rate of 35% per couple and only three complications.

    Conclusions:

    • Electroejaculation (EEJ) combined with artificial insemination (AI) is an effective and safe treatment for male infertility stemming from neurogenic anejaculation.
    • The technique facilitates sperm retrieval for assisted reproductive technologies in men with conditions like SCI and post-RPLND.
    • Despite challenges with sperm quality, EEJ offers a viable pathway to fatherhood for affected individuals.