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[Alcohol consumption and its connection with mortality from cardiovascular diseases in 40-59 years old men (data from

A L Aleksandri, V V Konstantinov, A D Deev

    Terapevticheskii Arkhiv
    |February 13, 2004
    PubMed

    Insights

    Alcohol consumption contributes significantly to deaths from heart disease and stroke in working men. Moderate alcohol intake, up to 168 ml weekly, was associated with the lowest mortality risk in this cohort study.

    Area of Science:

    • Epidemiology
    • Public Health
    • Cardiovascular Research

    Context:

    • Investigating the impact of alcohol consumption (AC) on mortality rates.
    • Focusing on coronary heart disease (CHD), cerebral stroke (CS), cardiovascular diseases (CVD), and overall mortality (OM).
    • Utilizing data from a large-scale, long-term cohort study.

    Purpose:

    • To quantify the contribution of alcohol consumption to mortality from major cardiovascular and all-cause causes.
    • To identify potential thresholds or patterns of alcohol intake associated with varying mortality risks.
    • To inform public health strategies regarding alcohol consumption and cardiovascular health.

    Summary:

    • A 21.5-year cohort study of 7,815 working males (aged 40-59) in Moscow and St-Petersburg examined alcohol consumption's mortality impact.
    • Attributive risks for alcohol consumption were 16.6% for CHD, 14.8% for CS, 7.7% for CVD, and 11.9% for OM.
    • Lowest relative mortality risk for CHD, CVD, and OM was observed in men consuming a maximum of 168.0 ml of alcohol per week.

    Impact:

    • Highlights the significant attributable risk of alcohol consumption for major causes of mortality in middle-aged men.
    • Suggests a potential J-shaped or U-shaped relationship between alcohol intake and cardiovascular/overall mortality.
    • Underscores the need for nuanced public health recommendations on alcohol consumption, considering differential effects on various diseases.
    Abstract

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