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The Mouse Hindbrain As a Model for Studying Embryonic Neurogenesis
Published on: January 29, 2018
Early steps in the development of the forebrain
Stephen W Wilson1, Corinne Houart
1Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom. s.wilson@ucl.ac.uk
Abstract:
The tremendous complexity of the adult forebrain makes it a challenging task to elucidate how this structure forms during embryonic development. Nevertheless, we are beginning to understand how a simple epithelial sheet of ectoderm gives rise to the labyrinthine network of cells that constitutes the functional forebrain. Here, we discuss early events in forebrain development--those that lead to the establishment of the anterior neural plate and the regional subdivision of this territory into the different domains of the prospective forebrain.
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