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Updated: Aug 26, 2026

A Modified Simple Method for Induction of Myocardial Infarction in Mice
Published on: December 3, 2021
Comparative study of smokers, ex-smokers, and nonsmokers who have experienced myocardial infarction
Diogo Nozawa1, Roberto Alexandre Franken, Karina de Cássia Braga Ribeiro
1Santa Casa de Misericórdia de São Paulo, Brasil.
Objective:
To assess the impact of smoking on in-hospital morbidity and mortality in patients who have experienced acute myocardial infarction and to assess the association between smoking and other cardiovascular risk factors and clinical data.
Methods:
A prospective cohort study analyzed 121 patients, including 54 smokers, 35 ex-smokers, and 32 nonsmokers.
Results:
Using the chi-square test (P<0.05), an association between smoking and the risk factors sex, age, and diabetes was documented. Among the morbidity and mortality variables, only acute pulmonary edema showed a statistically significant difference (OR=9.5; 95% CI), which was greater in the ex-smoker group than in the nonsmoker group.
Conclusion:
An association between smoking and some cardiovascular risk factors was observed, but no statistical difference in morbidity and mortality was observed in the groups studied, except for the variable acute pulmonary edema.
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