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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Vancomycin-induced linear IgA bullous dermatosis: morphology is a key to diagnosis
Benjamin A Solky1, Laura Pincus, Richard F Horan
1Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA. bsolky@partners.org
Abstract:
Vancomycin-induced linear IgA bullous dermatosis (LABD) previously has been described; however, past reports have suggested that the clinical presentation is nonspecific. We present a case of vancomycin-induced LABD with a suggestive clinical presentation; specifically, groups of annularly arranged vesicles. We propose that this clinical presentation strongly suggests drug-induced LABD and should raise a clinician's suspicion of vancomycin as the offending agent. This awareness may guide the antibiotic management of the patient while the clinician awaits histopathologic correlation.
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