Related Experiment Video

Updated: Aug 26, 2026

A Mouse Model of Intestinal Partial Obstruction
07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

[Morphological characteristics of inflammatory polyps of the large intestine in children]

A S Tertychnyĭ1

  • 1Russian State Medical University, 117869, Moscow.

Arkhiv Patologii
|February 18, 2004
PubMed

Insights

Inflammatory polyps are common in children, often found in the rectum. Morphologically, they are characterized by granulation tissue, distinguishing them from juvenile polyps.

Area of Science:

  • Pediatric pathology
  • Gastrointestinal diseases

Context:

  • Inflammatory polyps are a significant finding in pediatric colorectal pathology.
  • From 1983-2002, they constituted over 20% of all removed polyps in children, ranking second after juvenile polyps.

Purpose:

  • To describe the morphological characteristics of inflammatory polyps in children.
  • To differentiate inflammatory polyps from other pediatric polyp types, particularly juvenile polyps.

Summary:

  • Morphological study of 32 pediatric inflammatory polyps.
  • Predominant feature is granulation tissue, lacking glands but potentially containing foreign bodies and giant cells.
  • Associated mucosal prolapse syndrome observed in one-third of cases, indicated by smooth muscle cell and fibrous tissue proliferation.

Impact:

  • Provides key diagnostic features for differentiating pediatric inflammatory polyps.
  • Highlights the association with mucosal prolapse syndrome, aiding in comprehensive patient assessment.

More Related Videos

Studying the Epithelial Effects of Intestinal Inflammation In Vitro on Established Murine Colonoids06:31

Studying the Epithelial Effects of Intestinal Inflammation In Vitro on Established Murine Colonoids

Published on: June 2, 2023

Related Concept Videos

Histology of the Small Intestine01:27

Histology of the Small Intestine

The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Histology of the Large Intestine01:26

Histology of the Large Intestine

The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...