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Related Experiment Videos

Colonic transit time--what is normal?

S Wagener1, K R Shankar, R R Turnock

  • 1Alder Hey Children's Hospital, Liverpool England, UK.

Journal of Pediatric Surgery
|February 18, 2004
PubMed
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Colonic transit time (CTT) measurement in children provides an objective assessment for constipation. This study establishes normal CTT values in healthy pediatric patients using Abrahamsson's method, aiding in diagnosis.

Area of Science:

  • Pediatric Gastroenterology
  • Radiology
  • Digestive Motility Disorders

Background:

  • Childhood constipation is prevalent, with limited data on normal colonic transit time (CTT) in pediatric populations.
  • Radiologic methods for investigating constipation in children are varied, but CTT assessment is under-explored.
  • Objective measures for evaluating colonic motility in children are scarce.

Purpose of the Study:

  • To establish normal colonic transit time (CTT) values in a healthy pediatric cohort.
  • To evaluate the utility of Abrahamsson's method for CTT measurement in children.
  • To provide reference data for diagnosing pediatric constipation.

Main Methods:

  • Colonic transit time (CTT) was measured in 22 healthy children (median age 10 years) using Abrahamsson's method.

Related Experiment Videos

  • Radiopaque markers were ingested daily for 6 days, followed by an abdominal X-ray on day 7.
  • Total and segmental colonic transit times were calculated.

    • Main Results:

    • The mean total CTT was 40 hours, with an upper limit of normal (95th percentile) of 84 hours.
    • Normal upper limits for segmental transit times were established: ascending colon (14 hours), transverse colon (33 hours), descending colon (21 hours), and rectosigmoid colon (41 hours).

    Conclusions:

    • Colonic transit time (CTT) offers an objective method for assessing childhood constipation.
    • Abrahamsson's method is well-tolerated, involves low radiation exposure, and provides valuable normal CTT values for children.
    • This study contributes essential normative data for pediatric CTT assessment.