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The Leiden Early Arthritis Clinic.

J van Aken1, J H van Bilsen, C F Allaart

  • 1Leiden University Medical Center, Leiden, The Netherlands.

Clinical and Experimental Rheumatology
|February 19, 2004
PubMed
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The Early Arthritis Clinic (EAC) aids in early detection and treatment of inflammatory arthritis, particularly rheumatoid arthritis. Research from the EAC database significantly impacts clinical practice and ongoing studies.

Area of Science:

  • Rheumatology
  • Immunology
  • Clinical Research

Background:

  • Established in 1993, the Early Arthritis Clinic (EAC) at Leiden University Medical Center focuses on early detection and treatment of inflammatory disorders.
  • The clinic specifically targets early rheumatoid arthritis, enrolling patients with recent-onset arthritis (less than 2 years).

Purpose of the Study:

  • To review research findings from the EAC database over the past decade.
  • To highlight the relevance of EAC-generated reports for clinical practice and scientific investigation.
  • To emphasize the importance of the EAC framework for future arthritis research.

Main Methods:

  • Patients with confirmed recent-onset arthritis were enrolled by rheumatologists and research nurses.
  • Data collected included medical history, physical examinations, laboratory tests, questionnaires, radiographic scores, and diagnoses.

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  • A comprehensive EAC database was utilized for research purposes.

    • Main Results:

    • Reports from the EAC have been highly relevant to both daily clinical practice and research over the last ten years.
    • Studies have investigated cellular immunology, genetic, environmental, and clinical risk factors for inflammatory arthritis.
    • The EAC facilitates diverse research avenues, including pathophysiological mechanism determination.

    Conclusions:

    • The EAC provides a crucial framework for advancing arthritis research.
    • Continued research within the EAC setting is vital for understanding and managing inflammatory arthritis.
    • Past and future studies underscore the enduring significance of the EAC.