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Effect of Ha-ras on mitogen-induced Ca(2+)- and K(+)-fluxes
1Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Austria.
Advances in Enzyme Regulation
|January 1, 1992
Abstract:
Transforming Ha-ras enhances the mitogen-induced activation of both the Ca(2+)-influx and the furosemide-sensitive Na+/K+/2Cl-cotransporter. Both systems represent essential early steps of mitogenic signal transduction in NIH 3T3 fibroblasts.