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Updated: Aug 26, 2026
Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
Sonographic characteristics of peripheral nerve sheath tumors
David L Reynolds1, Jon A Jacobson, Prasuna Inampudi
1Department of Radiology, University of Michigan Medical Center, 1500 E Medical Center Drive, TC 2910G, Ann Arbor, MI 48109-0326, USA.
Objective:
We have found variability in the sonographic appearance of peripheral nerve sheath tumors. The purpose of this study was to characterize the sonographic appearances of pathologically proven peripheral nerve sheath tumors.
Conclusion:
Peripheral nerve sheath tumors are often hypoechoic with posterior acoustic enhancement and so may simulate a ganglion cyst. The presence of intrinsic blood flow on color Doppler sonography and peripheral nerve continuity suggests the diagnosis of peripheral nerve sheath tumor. Sonography cannot reliably distinguish neurofibromas from schwannomas.