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Updated: Jul 19, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
Published on: February 28, 2013
Role of oral anti-diabetic agents in modifying cardiovascular risk factors
1Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine at SUNY Downstate Medical Center, and Veterans Adminsitration Medical Center of Brooklyn, New York 11203, USA. jshin@yahoo.com
Abstract:
Patients with type 2 diabetes have an increased risk for cardiovascular disease (CVD) and it accounts for up to 80% of excess deaths in these patients. It has been recognized that type 2 diabetes is associated with an increased prevalence of CVD risk factors, including hypertension, dyslipidemia, microalbuminuria, and altered hemostasis. The benefit of cardiovascular protection can only be partially explained by controlling hyperglycemia. Some of the oral agents used to treat hyperglycemia significantly modify other cardiovascular risk factors. This article will review oral agents used to treat type 2 diabetes and their effects on modifying CVD risk factors.
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