Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:

Esophageal Strictures-II: Clinical Features and Management

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

Pneumothorax II: Pathophysiology

Pneumothorax II: Pathophysiology

Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Electronic Nicotine Delivery Systems and Clinical Outcomes in Adults With Inflammatory Bowel Disease: A Systematic Review of Emerging Evidence.

Cureus·2026

Same author

Vonoprazan vs Proton Pump Inhibitors for Gastroprotection in Anticoagulated Patients: A Real-World Cohort Study.

Cureus·2026

Same author

Synergistic Organic-Inorganic Interface Engineering for Stable Zinc Metal Anodes in Aqueous Batteries.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Comparative Outcomes of Arthroscopic Versus Open Meniscus Repair: An Observational Study.

Journal of orthopaedic case reports·2026

Same author

Retrograde Intramedullary Nailing Versus Locked Plating for Periprosthetic Distal Femur Fractures: A Propensity-matched Cohort from TriNetX.

Journal of orthopaedic case reports·2026

Same author

Trends in Rheumatoid Arthritis Mortality in the United States, 1999-2020.

Journal of orthopaedic case reports·2026

Search research articles

Related Experiment Video

Updated: May 2, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

Mediastinal compression secondary to supraglottitis: a case report.

Aamir Shahzad¹

¹Department of Otolaryngology, St. Michael's Hospital, Bristol, United Kingdom. mera_nam@yahoo.co.uk

American Journal of Otolaryngology

|February 21, 2004

Summary

Supraglottitis rarely spreads to neck fascial spaces and the mediastinum. This case highlights a patient’s recovery from mediastinal edema and hemodynamic compromise without aggressive surgery.

More Related Videos

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

Published on: November 28, 2025

Related Experiment Videos

Last Updated: May 2, 2026

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing

Published on: December 1, 2023

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

Published on: November 28, 2025

Area of Science:

Otolaryngology
Thoracic Surgery
Infectious Disease

Background:

Fascial spaces in the neck can allow infections to spread to the mediastinum.
Supraglottitis (inflammation of the area above the vocal cords) typically does not spread to these spaces.

Observation:

A rare case of supraglottitis spreading to the parapharyngeal space and subsequently to the mediastinum was observed.
The mediastinal edema caused increased intrathoracic pressure, leading to hemodynamic instability and pulmonary edema.

Findings:

The patient presented with critical symptoms including pulmonary edema and hypotension.
Recovery was achieved without the need for aggressive surgical interventions typically recommended for such severe infections.

Implications:

This case demonstrates a rare but serious complication of supraglottitis.
Conservative management may be successful in select cases of mediastinal spread, challenging current surgical recommendations.