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Electrochemical DNA array for simultaneous genotyping of single-nucleotide polymorphisms associated with the

Masayoshi Takahashi1, Jun Okada, Keiko Ito

  • 1Toshiba Research & Development Center, 1, Komukai Toshiba-cho, Saiwai-ku, Kawasaki, Kanagawa 212-8582, Japan. masayoshi8.takahashi@toshiba.co.jp

Clinical Chemistry
|February 26, 2004
PubMed
Abstract

No abstract available in PubMed .

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...