Related Experiment Video
Updated: Jul 24, 2026

Microvascular Decompression: Salient Surgical Principles and Technical Nuances
Published on: July 5, 2011
Noninvasive linear accelerator radiosurgery as the primary treatment for trigeminal neuralgia
L Frighetto1, A A De Salles, Z A Smith
1Division of Neurosurgery, School of Medicine, University of California, Los Angeles, CA, USA.
Abstract:
The application of a dedicated linear accelerator (DLINAC) as a noninvasive surgical treatment for trigeminal neuralgia has not yet been demonstrated. This work evaluates the outcome and indications of 22 patients submitted to DLINAC radiosurgery as a primary treatment for essential trigeminal neuralgia. At last follow-up evaluation, 21 patients (95.5%) had sustained significant pain relief. DLINAC radiosurgery is safe and effective as a primary noninvasive surgical treatment for selected patients with essential trigeminal neuralgia.
Insights
Dedicated linear accelerator (DLINAC) radiosurgery offers effective, noninvasive treatment for trigeminal neuralgia. This study shows DLINAC radiosurgery provides significant pain relief for most patients as a primary treatment.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Trigeminal neuralgia is a debilitating neuropathic pain condition.
- Noninvasive surgical options are sought for essential trigeminal neuralgia treatment.
Purpose of the Study:
- To evaluate the efficacy and safety of dedicated linear accelerator (DLINAC) radiosurgery.
- To assess DLINAC radiosurgery as a primary treatment for essential trigeminal neuralgia.
Main Methods:
- Retrospective analysis of 22 patients with essential trigeminal neuralgia.
- Treatment with DLINAC radiosurgery as a primary intervention.
Main Results:
- Significant pain relief was achieved in 21 out of 22 patients (95.5%) at the last follow-up.
- DLINAC radiosurgery demonstrated a high success rate in pain management.
Conclusions:
- DLINAC radiosurgery is a safe and effective primary treatment option.
- Selected patients with essential trigeminal neuralgia can benefit from DLINAC radiosurgery.

