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SU-E-T-386: Gamma Analysis of Normalized and Un-Normalized Dose Distributions.

S Stojadinovic1, O Luo1, Q Bao1

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Summary
This summary is machine-generated.

The gamma index method for radiation dose QA needs no normalization point for unique results. However, standard 3%/3 mm criteria are inadequate without normalization, requiring re-evaluation for accurate dose distribution agreement.

Keywords:
Computer softwareData analysisIonization chambersLinear acceleratorsNumerical solutionsPhotonsTherapeutics

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Quality Assurance

Background:

  • Current gamma index methods in commercial QA software require selecting a normalization point.
  • This normalization point choice leads to multiple possible solutions for dose distribution agreement.
  • A unique solution is achieved by omitting the normalization point.

Purpose of the Study:

  • To evaluate the impact of using a normalization point versus no normalization point in the gamma index method.
  • To assess the agreement between calculated and delivered dose distributions using AAPM TG119 test cases and clinical data.
  • To determine the suitability of common gamma index criteria (3%/3 mm) without normalization.

Main Methods:

  • AAPM TG119 test cases were planned and delivered using Pinnacle 8.0m and a Varian 21EX linac (6 and 18 MV photons).
  • Point and planar dose measurements were performed using ion chamber, film, and MatriXX.
  • Gamma index analysis (3%/3 mm) was conducted with and without a normalization point on both benchmark and clinical data.

Main Results:

  • With normalization, gamma passing rates for TG119 complex tests were high (95.8±1.6% for 6 MV, 95.6±1.0% for 18 MV).
  • Without normalization, gamma passing rates significantly dropped (20.7±6.7% for 6 MV, 13.9±4.0% for 18 MV).
  • Clinical data showed a similar trend, with passing rates decreasing from 98.9±0.7% to 33.4±13.1% without normalization.

Conclusions:

  • The gamma index method yields a unique gamma passing rate solely when dose distributions are not normalized.
  • The standard 3%/3 mm gamma criteria is an insufficient metric when no normalization point is used.
  • Further investigation into appropriate gamma criteria for non-normalized dose comparisons is warranted.