Is cardiac IKs a relevant drug target?

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Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy.

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Timing of food intake impacts cardiovascular and neuroendocrine physiology and risk of disease.

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Dual inhibition of SGLT 1 and 2 by sotagliflozin alleviates intracellular sodium overload and improves cardiometabolic remodelling in uraemic cardiomyopathy.

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Liver sinusoidal endothelial cell (LSEC) defenestration in chronic heart failure is primarily dependent on cardiac diastolic dysfunction and is reversed by sodium-glucose cotransporter 2 inhibitor but not by angiotensin-converting enzyme inhibitor.

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Related Experiment Videos

Is cardiac IKs a relevant drug target?

Related Concept Videos

Signal detection and characterisation of a novel drug-drug interaction between methadone and a synthetic cannabinoid receptor agonist.

Advancing safety pharmacology: Emerging technologies, innovative methods, and future directions.

Diltiazem N-oxide, a novel ischaemia-activated prodrug, prevents ischaemia-induced ventricular fibrillation without off-target adverse effects.

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Be CLEAR to ensure methodological and data transparency.

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Dual inhibition of SGLT 1 and 2 by sotagliflozin alleviates intracellular sodium overload and improves cardiometabolic remodelling in uraemic cardiomyopathy.

Liver sinusoidal endothelial cell (LSEC) defenestration in chronic heart failure is primarily dependent on cardiac diastolic dysfunction and is reversed by sodium-glucose cotransporter 2 inhibitor but not by angiotensin-converting enzyme inhibitor.

Polycystin-1 suppresses apoptotic signalling in endothelial cells and protects from atherosclerosis.

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Is cardiac IKs a relevant drug target?

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