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Epidemiology considerations in peptic ulcer disease
P K Schlesinger1, B Robinson, T J Layden
1Department of Medicine, Veterans Administration West Side Medical Center, Chicago, IL.
Journal of the Association for Academic Minority Physicians : the Official Publication of the Association for Academic Minority Physicians
|January 1, 1992
Summary
Peptic ulcer disease affects millions annually, posing a significant economic burden. While hospitalization and mortality rates have declined, understanding its evolving epidemiology is crucial for effective treatment and identifying causes.
Area of Science:
- Gastroenterology
- Epidemiology
Background:
- Peptic ulcer disease (PUD) is a prevalent clinical issue with a lifetime risk of at least 10%.
- Millions are affected annually, contributing to a substantial economic burden on healthcare.
- While overall hospitalization and mortality rates for PUD have decreased, this trend predates effective medical therapies.
Purpose of the Study:
- To analyze the changing epidemiology of peptic ulcer disease.
- To understand the impact of various factors on PUD trends.
- To inform future assessments of medical and surgical therapies and etiological research.
Main Methods:
- Review of epidemiological trends in peptic ulcer disease.
- Analysis of factors influencing PUD prevalence and outcomes.
- Examination of hospitalization and mortality data over recent decades.
Main Results:
- Overall hospitalization and mortality rates for PUD have declined over past decades.
- Factors like an aging population, smoking prevalence, and NSAID use influence PUD epidemiology.
- Hospitalization rates for PUD complications remain stable, with increases in elderly women with gastric ulcers.
Conclusions:
- Understanding PUD epidemiology is vital for evaluating therapeutic interventions.
- Further research into the etiology of PUD is warranted.
- Shifting demographics and drug use patterns impact PUD trends.