Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The p38 MAP kinase pathway and its biological function.

L New1, J Han

  • 1Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA.

Trends in Cardiovascular Medicine
|February 28, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inductively-coupled control unit for fully implantable middle ear hearing devices.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2007
Same author

Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody.

Neuroscience·2007
Same author

Fine needle aspiration cytology of solitary fibrous tumours of the pleura.

Cytopathology : official journal of the British Society for Clinical Cytology·2007
Same author

Creutzfeldt-Jakob disease in a Chinese patient with a novel seven extra-repeat insertion in PRNP.

Journal of neurology, neurosurgery, and psychiatry·2007
Same author

Endoscopic removal of biliary self-expandable metallic stents: a prospective study.

Endoscopy·2006
Same author

Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans.

Journal of human hypertension·2006
Same journal

Artificial Intelligence in Echocardiography for Valvular Heart Disease.

Trends in cardiovascular medicine·2026
Same journal

Inflammation as a Fulcrum in Cardiovascular Disease: The Evolving Case for High-Sensitivity C-Reactive Protein.

Trends in cardiovascular medicine·2026
Same journal

Comment on "advancing personalised care in atrial fibrillation and stroke: The potential impact of AI from prevention to rehabilitation".

Trends in cardiovascular medicine·2026
Same journal

Response to: Comment on "Advancing personalised care in atrial fibrillation and stroke: The potential impact of AI from prevention to rehabilitation" (TCM-D-26-00198).

Trends in cardiovascular medicine·2026
Same journal

High-sensitivity C-reactive protein as a prognostic biomarker in cardiovascular diseases: implications for atherosclerosis, chronic kidney disease, and heart failure - a review.

Trends in cardiovascular medicine·2026
Same journal

The cost of false dichotomies in a dynamic disease.

Trends in cardiovascular medicine·2026
See all related articles

The p38 mitogen-activated protein (MAP) kinase pathway is activated by stress and inflammation. Its dysregulation is linked to inflammatory and cardiovascular diseases.

Area of Science:

  • Cellular signaling and molecular biology
  • Biochemistry and immunology

Background:

  • p38 is a distinct mitogen-activated protein (MAP) kinase.
  • Its activity increases in response to various cellular stressors and inflammatory signals.
  • p38 plays a role in signal transduction pathways.

Purpose of the Study:

  • To elucidate the role of the p38 MAP kinase pathway in cellular responses.
  • To understand the involvement of p38 in disease pathogenesis.

Main Methods:

  • The abstract does not specify methods.
  • Focuses on the known functions and implications of p38 MAP kinase.

Main Results:

  • p38 MAP kinase regulates downstream substrates like protein kinases and transcription factors.

Related Experiment Videos

  • Activation of the p38 pathway is associated with inflammatory/immunologic diseases.
  • p38 pathway activation is implicated in cardiovascular diseases.

    • Conclusions:

    • The p38 pathway is a key mediator of cellular responses to stress and inflammation.
    • Dysregulation of p38 signaling contributes to the pathology of inflammatory and cardiovascular conditions.