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Updated: Aug 12, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
[Surgery for multiple myeloma of the bone]
Xi-cheng Li1, Wei Guo, Rong-li Yang
1Department of Orthopaedics, People's Hospital, Beijing University, Beijing 100044, China.
Surgical treatment for bone multiple myeloma relieved pain and improved neurological function in patients. This approach may be beneficial in select cases, despite a low rate of local recurrence.
Area of Science:
- Orthopedic Oncology
- Surgical Oncology
- Hematologic Oncology
Context:
- Multiple myeloma can affect the bone, leading to pain and neurological deficits.
- Surgical intervention is considered for palliative and reconstructive purposes in these cases.
Purpose:
- To evaluate the indications, surgical approaches, and outcomes of treating bone multiple myeloma.
- To assess pain relief, neurological improvement, quality of life, and survival post-surgery.
Summary:
- Twenty-nine patients with bone multiple myeloma underwent surgical treatment between 1997 and 2002.
- Surgical procedures included tumor resection, stabilization, endoprosthetic replacement, and fracture fixation.
- All patients experienced pain relief, and neurological function improved post-operatively, with three cases of local recurrence.
Impact:
- Surgical treatment can effectively alleviate symptoms associated with bone multiple myeloma.
- The findings suggest that surgical intervention can be a rewarding option for select patients with multiple myeloma affecting the bone.
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