Related Experiment Video

Updated: Aug 26, 2026

Drosophila Passive Avoidance Behavior as a New Paradigm to Study Associative Aversive Learning
06:20

Drosophila Passive Avoidance Behavior as a New Paradigm to Study Associative Aversive Learning

Published on: October 15, 2021

Inhibiting effect of D1, but not D2 antagonist administered to the striatum on retention of passive avoidance in the

Peter Kabai1, Michael G Stewart, József Tarcali

  • 1Department of Ecology, Faculty of Veterinary Science, Szent István University, H-1400 Budapest, PO Box 2, Hungary. pkabai@univet.hu

Neurobiology of Learning and Memory
|March 3, 2004
PubMed

More Related Videos

Straightforward Assay for Quantification of Social Avoidance in Drosophila melanogaster08:08

Straightforward Assay for Quantification of Social Avoidance in Drosophila melanogaster

Published on: December 13, 2014

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

Related Concept Videos

Indirect-Acting Cholinergic Agonists: Mechanism of Action01:18

Indirect-Acting Cholinergic Agonists: Mechanism of Action

Indirect-acting cholinergic agonists work by interacting with an enzyme called acetylcholinesterase (AChE) in the synaptic cleft. They can be reversible or irreversible inhibitors and have different effects on the enzyme.
Reversible inhibitors like edrophonium bind to a specific part of the enzyme called the anionic catalytic site. They form noncovalent bonds, which means they are not strongly attached to the enzyme. This creates a temporary and less stable enzyme–inhibitor complex, leading to...
Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship01:29

Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
Reversible inhibitors display short to medium durations of action. Short-acting agents include simple alcohols with...
Direct-Acting Cholinergic Agonists: Pharmacokinetics01:31

Direct-Acting Cholinergic Agonists: Pharmacokinetics

Direct-acting cholinergic agonists, such as synthetic choline esters and naturally occurring alkaloids, exert their effects by enhancing the actions of acetylcholine and stimulating the parasympathetic nervous system. Synthetic choline esters share structural similarities with acetylcholine. For example, they have a positively charged quaternary ammonium or onium group, contributing to their hydrophilic characteristics. As a result, they are poorly absorbed in the body through oral...