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Updated: Aug 15, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Prognostic differences between atrial fibrillation and atrial flutter
Paul Lelorier1, Karin H Humphries, Andrew Krahn
1Division of Cardiology, University of Western Ontario, London, Ontario, Canada. paul.lelorier@bmc.org
Insights
This study analyzed 94 patients with atrial fibrillation, focusing on stroke and death risks. Warfarin use and left atrial dimensions were also evaluated in this Canadian Registry of Atrial Fibrillation cohort.
Area of Science:
- Cardiology
- Clinical Research
- Epidemiology
Background:
- Atrial fibrillation (AF) is a common arrhythmia associated with increased risk of stroke and death.
- Understanding the long-term outcomes and management of AF patients is crucial for improving clinical practice.
- The Canadian Registry of Atrial Fibrillation provides a valuable dataset for such investigations.
Purpose of the Study:
- To report the outcomes of a cohort of 94 patients with atrial fibrillation.
- To specifically assess the probability of stroke and death in this patient group.
- To evaluate warfarin use patterns and compare left atrial dimensions between atrial flutter and atrial fibrillation.
Main Methods:
- Retrospective analysis of a cohort from the Canadian Registry of Atrial Fibrillation.
- Inclusion of 94 patients diagnosed with atrial fibrillation.
- Assessment of stroke and death probabilities, warfarin utilization, and left atrial dimensions.
Main Results:
- The study details the observed stroke and death probabilities within the cohort.
- Analysis of warfarin use trends over the study period is presented.
- Comparison of left atrial dimensions between patients with atrial flutter and atrial fibrillation is provided.
Conclusions:
- The findings contribute to understanding the risks associated with atrial fibrillation.
- The data offers insights into warfarin management in AF patients.
- Comparative analysis of atrial dimensions may inform differential diagnosis and prognosis.
Abstract:
This report presents the outcome of a cohort of 94 patients with atrial fibrillation from the Canadian Registry of Atrial Fibrillation, in which we paid particular attention to the probability of stroke and death. We also evaluated warfarin use over time and compared left atrial dimensions in patients with atrial flutter with those with atrial fibrillation.
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