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[Atypical and malignant intracranial meningiomas]
M Gelabert-González1, J M Fernández-Villa, M Iglesias-Pais
1Instituto Universitario de Ciencias Neurológicas Pedro Barrié de la Maza, Universidad de Santiago de Compostela, España. cimigego@usc.es
Revista De Neurologia
|March 5, 2004
Summary
Malignant meningiomas, though rare, require aggressive treatment. Complete surgical resection and adjuvant radiotherapy are crucial for long-term control in these aggressive brain tumors.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Context:
- Meningiomas are common central nervous system tumors, typically benign (WHO grade I).
- However, certain histological subtypes (WHO grades II and III) are aggressive and associated with poor outcomes.
- Malignant meningiomas represent 1-10% of all meningiomas.
Purpose:
- To review the epidemiology, clinical presentation, surgical management, and histological characteristics of multiple intracranial meningiomas.
- To analyze outcomes for patients with malignant intracranial meningiomas.
Summary:
- This study reviewed 12 cases of malignant intracranial meningiomas treated between 1985-2002.
- Atypical meningiomas were the most common subtype (5 cases). Median survival was 48 months.
- Complete surgical resection combined with adjuvant radiotherapy is essential for managing malignant meningiomas.
Impact:
- Highlights the importance of multimodal treatment for aggressive meningiomas.
- Informs clinical decision-making for neurosurgeons and oncologists.
- Contributes to understanding the prognosis of malignant meningiomas.