Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A childhood cavernous conundrum.

Andrew G Lee1, Susan J Quick, Grant T Liu

  • 1Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.

Survey of Ophthalmology
|March 5, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Apraxia of lid opening in multiple sclerosis.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2022
Same author

Sphenoid Sinusitis-Associated Optic Neuropathy: A Forgotten Disease.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

Posterior Ischemic Optic Neuropathy Following Recurrent COVID-19 in Prior Bilateral Sequential Nonarteritic Anterior Ischemic Optic Neuropathy.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

Optic nerve sheath diameter and spaceflight: defining shortcomings and future directions.

NPJ microgravity·2022
Same author

Progressive Optic Neuropathy in Cerebellar Ataxia, Areflexia, Optic Atrophy, and Sensorineural Hearing Loss Syndrome: The Importance of Targeted Gene Testing.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

Visual Loss as the Presenting Manifestation of Leptomeningeal Spread of Glioblastoma Multiforme to the Optic Chiasm.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same journal

Trends in pediatric uveitis: A systematic review and meta-epidemiological investigation of geographic, economic, and climate factors.

Survey of ophthalmology·2026
Same journal

Efficacy and safety of different intraocular therapies for non-infectious uveitis: A network meta-analysis.

Survey of ophthalmology·2026
Same journal

Macular telangiectasia masqueraders.

Survey of ophthalmology·2026
Same journal

Utilization of anterior segment optical coherence tomography in childhood glaucoma: A systematic review.

Survey of ophthalmology·2026
Same journal

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026
Same journal

Prognostic factors and postoperative outcomes in pediatric cataract patients: A systematic review and meta-analysis.

Survey of ophthalmology·2026
See all related articles

Burkitt lymphoma, a rare cancer, can mimic cavernous sinus thrombosis in children. Early diagnosis and chemotherapy led to a child's recovery from a rare presentation of third nerve palsy.

Area of Science:

  • Pediatric Oncology
  • Neurology
  • Ophthalmology

Background:

  • Cavernous sinus syndrome (CSS) in children is rare and can be caused by various conditions, including infections and malignancies.
  • Cranial nerve palsies, particularly involving the oculomotor nerve (CN III), can be presenting symptoms of CSS.

Observation:

  • A 9-year-old boy presented with toothache and new-onset vertical diplopia, indicating a left CN III palsy.
  • Cranial MRI revealed bilateral cavernous sinus lesions initially suspected as thrombosis.
  • Blood smear and bone marrow biopsy confirmed Burkitt lymphoma as the underlying cause.

Findings:

  • Burkitt lymphoma, a highly aggressive non-Hodgkin lymphoma, uncommonly presents as CSS with CN III palsy in pediatric cases.
  • The patient experienced a dramatic recovery following chemotherapy treatment for Burkitt lymphoma.

Related Experiment Videos

Implications:

  • This case highlights the importance of considering hematologic malignancies, specifically Burkitt lymphoma, in the differential diagnosis of pediatric CSS.
  • Prompt diagnosis and treatment of Burkitt lymphoma are crucial for favorable outcomes in children presenting with neurological symptoms.
  • Further research into rare presentations of pediatric malignancies can improve diagnostic accuracy and patient management strategies.