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Updated: Aug 7, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
Functional neuroimaging of social cognition in pervasive developmental disorders: a brief review
Adriana Di Martino1, F Xavier Castellanos
1New York University Child Study Center, 577 First Avenue, New York, NY 10016, USA.
Abstract:
An emerging literature on the neuroanatomical correlates of social cognition in pervasive developmental disorders is reviewed. Studies conducted with high-functioning adults with autism or Asperger's syndrome highlight patterns of decreased activation in ventromedial prefrontal cortex, temporo-parietal junction, amygdala, and periamygdaloid cortex, along with aberrantly increased activation in primary sensory cortices. Future studies should extend these important initial results to younger and more severely affected subjects.
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