Related Experiment Video
Updated: Jul 21, 2026

Psychophysiological Stress Assessment Using Biofeedback
Published on: July 31, 2009
Biofeedback treatment increases heart rate variability in patients with known coronary artery disease
Jessica M Del Pozo1, Richard N Gevirtz, Bret Scher
1California School of Professional Psychology at Alliant International University, San Diego, Calif 9213, USA.
Insights
Cardiorespiratory biofeedback significantly increases heart rate variability (HRV) in patients with coronary artery disease (CAD). This intervention may improve cardiac outcomes and reduce mortality rates in this population.
Area of Science:
- Cardiology
- Biofeedback
- Physiology
Background:
- Diminished heart rate variability (HRV) is linked to increased cardiac morbidity and mortality.
- Lifestyle changes and pharmacologic therapies can potentially improve HRV.
- Biofeedback presents a novel approach to enhance HRV in cardiac patients.
Purpose of the Study:
- To investigate the efficacy of cardiorespiratory biofeedback in increasing HRV.
- To assess the impact of biofeedback on patients with documented coronary artery disease (CAD).
Main Methods:
- Sixty-three patients with established CAD were randomized to either conventional therapy or 6 biofeedback sessions.
- Biofeedback included abdominal breath training and cardiorespiratory feedback.
- HRV was measured using standard deviation of normal-to-normal QRS complexes (SDNN) at baseline, 6 weeks, and 18 weeks.
Main Results:
- The biofeedback group demonstrated a significant increase in SDNN from baseline to week 6 (P <.001) and week 18 (P =.003).
- No significant changes in SDNN were observed in the control group at week 6 (P =.214) or week 18 (P =.27).
- SDNN differed significantly between groups at week 18.
Conclusions:
- Cardiorespiratory biofeedback is effective in increasing HRV in patients with CAD.
- Biofeedback may serve as a valuable tool for improving cardiac health and reducing mortality.
- Further research is warranted to explore biofeedback's role in cardiac rehabilitation.
Objectives:
To determine if cardiorespiratory biofeedback increases heart rate variability (HRV) in patients with documented coronary artery disease (CAD).
Background:
Diminished HRV has been associated with increased cardiac morbidity and mortality. Evidence suggests that various lifestyle changes and pharmacologic therapies can improve HRV. The objective of this study was to determine if biofeedback increases HRV in patients with CAD.
Methods:
Patients with established CAD (n = 63; mean age, 67 years) were randomly assigned to conventional therapy or to 6 biofeedback sessions consisting of abdominal breath training, heart and respiratory physiologic feedback, and daily breathing practice. HRV was measured by the standard deviation of normal-to-normal QRS complexes (SDNN) at week 1 (pretreatment), week 6 (after treatment), and week 18 (follow-up).
Results:
Baseline characteristics were similar for the treatment and control groups. The SDNN for the biofeedback and control groups did not differ at baseline or at week 6 but were significantly different at week 18. The biofeedback group showed a significant increase in SDNN from baseline to week 6 (P <.001) and to week 18 (P =.003). The control subjects had no change from baseline to week 6 (P =.214) and week 18 (P =.27).
Conclusions:
Biofeedback increases HRV in patients with CAD and therefore may be an integral tool for improving cardiac morbidity and mortality rates.
Related Concept Videos
Increased pulse rate
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Decreased pulse rate
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with bradycardia...
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...

