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Updated: Aug 26, 2026

Assessment of Kidney Function in Mouse Models of Glomerular Disease
Published on: June 30, 2018
Urinary albumin in space missions
Massimo Cirillo1, Natale G De Santo, Martina Heer
1Nephrology-Second University of Naples, Naples, Italy. massimo.cirillo@unina2.it
Abstract:
Proteinuria was hypothesized for space mission but research data are missing. Urinary albumin, as index of proteinuria, was analyzed in frozen urine samples collected by astronauts during space missions onboard MIR station and on ground (control). Urinary albumin was measured by a double antibody radioimmunoassay. On average, 24h urinary albumin was 27.4% lower in space than on ground; the difference was statistically significant. Low urinary albumin excretion could be another effect of exposure to weightlessness (microgravity).
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