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Updated: Aug 25, 2026
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Unresectable alpha fetoprotein-producing gastric cancer successfully treated with irinotecan and mitomycin C after
Ken Hirao1, Shoji Hirasaki, Takao Tsuzuki
1Department of Internal Medicine, National Shikoku Cancer Center, 13 Horino-uchi, Matsuyama 790-0007.
Abstract:
Diagnostic imaging of a 70-year-old woman revealed widespread lymph node swelling and pyloric stenosis due to alpha fetoprotein-producing gastric cancer. Second line chemotherapy of irinotecan and mitomycin C was administered after S-1 failure. After 6 courses of 2nd line chemotherapy, pyloric stenosis was improved, and lymph node swelling disappeared. This patient has been alive without disease for more than 3 years since 2nd line chemotherapy began and for more than 4 years since her first admittance to our hospital. Second line chemotherapy may have contributed to the favorable clinical outcome in this patient.
