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Updated: Jul 10, 2026

Isolating Nasal Olfactory Stem Cells from Rodents or Humans
Published on: August 22, 2011
Science imitates art: the cloning of mice from olfactory sensory neurons
1Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA.
Abstract:
The functional identity of an olfactory sensory neuron is defined by its expression of one odorant receptor from a large multigene family. The complexity of this process has led to speculation that DNA rearrangements are used to limit the expression of one receptor gene per cell. However, a recent report in Nature directly rules out irreversible DNA rearrangements as a mechanism for odorant receptor gene choice.
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