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Updated: Aug 14, 2026

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
Published on: February 22, 2020
Can SSEP results predict functional recovery of stroke patients within the "therapeutic window"?
Plamen Tzvetanov1, Ivan Milanov, Rossen T Rousseff
1Stroke Care Unit, Medical University of Pleven, Bulgaria. tzvetanovplamen@hotmail.com
Objectives:
To investigate the prognostic value of median somatosensory evoked potentials (mSSEP) within the "therapeutic window" of ischemic stroke.
Materials And Methods:
Twenty-two patients (mean age 60.8 +/- 14.8 years) with first ischemic stroke in middle cerebral artery territory without contraindications for thrombolysis underwent mSSEP investigation within 3 hours of onset. Stroke topography was verified within 48 hours by computed tomography. M-SSEP results (presence, amplitude and amplitude ratio, latency and central conduction time) were compared to severity of motor deficit at onset and to recovery at 6 months.
Results:
M-SSEP were present in 17 patients, 7 of whom had partial and 10--complete motor recovery. Absence of mSSEP was found in 5 persons. None recovered function of the arm and only 2 were ambulatory at 6 months.
Conclusions:
In the earliest phase of ischemic stroke absence of mSSEP response is reliable predictor of poor functional outcome.
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