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Identification of HLA-B*56 variant (B*560502) in the Korean population

C-W Pyo1, S-S Hur, D-W Kim

  • 1Catholic Hemopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, 505 Banpo-Dong, Seocho-Ku, Seoul 137-701, Korea.

Tissue Antigens
|March 11, 2004
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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...