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Morphometric ultrastructural analysis of satellite cells in denervated rat soleus muscle

Marek Kujawa1, Wojciech Baran, Ewa Jankowska-Steifer

  • 1Department of Histology and Embryology, Center of Biostructure Research, 02-004 Warsaw, Poland. mkujawa@ib.amwaw.edu.pl

Experimental and Molecular Pathology
|March 11, 2004
PubMed

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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...